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"GeneSpeed
BetaCell " is an extension of the GeneSpeed
Database. This data repository and bioinformatics toolbox
contains expression data and analysis tools specifically
designed for the study of pancreatic beta cells and their development.
The
GeneSpeed BetaCell is an array repository containing many
microarrays of pancreatic origin as well as an assortment of developmental
time series array data from a myriad of different tissues types. This
collection of developmental based array data has enabled us to develop
novel meta-analysis tools that analyze the differences in overall
tissue/organ developmental dynamics between different tissue/organ
types. Thus far, these new analyses have yielded novel insight into
the mechanisms and regulatory factors utilized by the pancreatic beta
cell.
Knowing that pancreatic development and beta-cell formation are
complex processes involving a multitude of genetic programs where
cell-to-cell signaling is critical, we have sought to include a variety
of gene expression information data in the database. This covers aspects
of pancreatic cell development, pancreatic cellular subtypes, endocrine,
exocrine and ductal cells, as well as providing information about
normal islet tissue. This data has been contributed by multiple investigators,
and the datasets are expected to grow to better cover more detailed
analyses of pancreatic cell differentiation. We encourage any investigator
to contribute to this compilation, and hereby expand and strengthen
the analyses that are available to the community.
Because our array repository contains data from many different
tissues/organs, this enables us to also analyze the developmental
details of other tissues as well. If you have performed microarrays
over many time points of a tissue/organ's developmental stages, we
would encourage you to share your data with us. By sharing your developmental
time series microarray data with us, we will provide you exclusive
access to the GeneSpeed BetaCell site, allowing you to conduct powerful
meta-analysis using all the arrays residing in our database on your
tissue of interest. If you are interested in sharing your microarray
data with us please contact us.
"Science is built up with facts, as a house is with stones. But a collection of facts is no more a science than a heap of stones is a house."
Jules Henri Poincaré (April 29, 1854 – July 17, 1912), In “La Science et l'Hypothèse” (1901).
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